ChagasDB

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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
ANXA6	annexin A6	ANXA6	cg18060909	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
ANXA6	annexin A6	ANXA6	cg20173654	Methylation	UP	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
ANXA9	annexin A9	ANXA9	cg13320146	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH	acyloxyacyl hydrolase	AOAH	ENSG00000136250	RNA	None	Cardiac	Nonesvg	Cardiac	None	Heart	Left ventricule	No	TFBS enrichment in JASPAR database	Yes	SPI1	ENSG00000066336	TFBS	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH	acyloxyacyl hydrolase	AOAH	cg06827792	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH	acyloxyacyl hydrolase	AOAH	cg14451276	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH	acyloxyacyl hydrolase	AOAH	cg25733272	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH	acyloxyacyl hydrolase	AOAH	ENSG00000136250	RNA	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	RNA-seq	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOAH-IT1	AOAH intronic transcript 1	AOAH-IT1	ENSG00000230539	RNA	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	RNA-seq	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOC1	amine oxidase copper containing 1	ABP1	cg08540215	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOC3	amine oxidase copper containing 3	AOC3	cg25512683	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg00214140	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg04134539	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg06596563	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg10407744	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg13761321	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg14078714	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg14582550	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg15895854	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
AOPEP	aminopeptidase O (putative)	C9orf3	cg16979165	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022

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