ChagasDB

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Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
MARS1 methionyl-tRNA synthetase 1 cg11575892 Methylation UP Cardiac Nonesvg Asymptomatic None Blood None No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
MARS1 methionyl-tRNA synthetase 1 cg14338062 Methylation DOWN Severe cardiac LVEF < 40%svg Moderate cardiac LVEF >= 40% Blood None No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
[ca2+]d Calcium concentration None Electrolyte UP Acute 50 dpisvg Acute 20 dpi Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[ca2+]d Calcium concentration None Electrolyte UP Chronic 120 dpisvg Acute 50 dpi Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[ca2+]d Calcium concentration None Electrolyte UP Acute 20 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[ca2+]d Calcium concentration None Electrolyte UP Acute 50 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[ca2+]d Calcium concentration None Electrolyte UP Chronic 120 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[na2+]d Calcium concentration None Electrolyte UP Acute 50 dpisvg Acute 20 dpi Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[na2+]d Calcium concentration None Electrolyte UP Chronic 120 dpisvg Acute 50 dpi Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[na2+]d Calcium concentration None Electrolyte UP Acute 20 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[na2+]d Calcium concentration None Electrolyte UP Acute 50 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
[na2+]d Calcium concentration None Electrolyte UP Chronic 120 dpisvg Healthy None Cardiomyocyte Cell culture Yes Microelectrodes No None None None Mus musculus C57BL/10 Y strain 35903196 10.3389/fcimb.2022.890709 The Role of the Na+/Ca2+ Exchanger in Aberrant Intracellular Ca2+ in Cardiomyocytes of Chagas-Infected Rodents 2022
2Methylcitrate 2 Methylcitrate None Chemical molecule DOWN Cardiac Nonesvg Healthy None Heart None Yes LC-MS No None None None Homo sapiens Colombia None 36142367 10.3390/ijms231810456 Metabolomic Profiling of End-Stage Heart Failure Secondary to Chronic Chagas Cardiomyopathy 2022
2PhosphoDglycerate 2 Phospho D glycerate None Chemical molecule UP Cardiac Nonesvg Healthy None Heart None Yes LC-MS No None None None Homo sapiens Colombia None 36142367 10.3390/ijms231810456 Metabolomic Profiling of End-Stage Heart Failure Secondary to Chronic Chagas Cardiomyopathy 2022
4Aminobutanoate 4 Aminobutanoate None Chemical molecule UP Cardiac Nonesvg Healthy None Heart None Yes LC-MS No None None None Homo sapiens Colombia None 36142367 10.3390/ijms231810456 Metabolomic Profiling of End-Stage Heart Failure Secondary to Chronic Chagas Cardiomyopathy 2022
5-Oxoproline 5-Oxoproline None Chemical molecule DOWN Cardiac Nonesvg Healthy None Heart None Yes LC-MS No None None None Homo sapiens Colombia None 36142367 10.3390/ijms231810456 Metabolomic Profiling of End-Stage Heart Failure Secondary to Chronic Chagas Cardiomyopathy 2022
A1BG-AS1 A1BG antisense RNA 1 cg25623524 Methylation UP Cardiac Nonesvg Healthy None Heart Left ventricule No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
A1BG-AS1 A1BG antisense RNA 1 cg12344206 Methylation DOWN Severe cardiac LVEF < 40%svg Moderate cardiac LVEF >= 40% Blood None No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
A1CF APOBEC1 complementation factor cg04167299 Methylation DOWN Cardiac Nonesvg Asymptomatic None Blood None No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
A1CF APOBEC1 complementation factor cg24726946 Methylation DOWN Cardiac Nonesvg Asymptomatic None Blood None No EPIC Illumina No None None None Homo sapiens Brazil None 36072583 10.3389/fimmu.2022.958200 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy 2022
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