ChagasDB

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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Edn1	endothelin 1 [Source:MGI Symbol;Acc:MGI:95283]	ET-1	ENSMUSG00000021367	RNA	UP	Acute	Nonesvg	Healthy	None	Heart	NA	Yes	RT-PCR	No	None	None	None	Mus musculus	CD1	Tulahuen	11064272	10.1016/s1054-8807(00)00045-4	Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection	2000
HLA-C	major histocompatibility complex, class I, C	HLA-C*03	HLA-C*03	Polymorphism	UP	Cardiac	Nonesvg	Asymptomatic	None	PBMC	NA	Yes	Hybridation	No	None	None	None	Homo sapiens	Venezuela	None	11053636	10.1016/s0198-8859(00)00161-0	HLA-C(*)03 is a risk factor for cardiomyopathy in Chagas disease	2000
HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	DRB1	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Serum	None	Yes	PCR	No	None	None	None	Homo sapiens	Peru	None	10777093	10.1034/j.1399-0039.2000.550301.x	HLA haplotypes are associated with differential susceptibility to Trypanosoma cruzi infection	2000
HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	DRB1	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Serum	None	Yes	Correlation	Yes	HLA-DQBI	DQB1*0301	Polymorphism	Homo sapiens	Peru	None	10777093	10.1034/j.1399-0039.2000.550301.x	HLA haplotypes are associated with differential susceptibility to Trypanosoma cruzi infection	2000
HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	DRB1	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Serum	None	Yes	Correlation	Yes	HLA-DQBI	DQB1*0503	Polymorphism	Homo sapiens	Peru	None	10777093	10.1034/j.1399-0039.2000.550301.x	HLA haplotypes are associated with differential susceptibility to Trypanosoma cruzi infection	2000
ICAM-1	intercellular adhesion molecule 1	ICAM-1	ENSG00000090339	Protein	UP	Cardiac	Nonesvg	Healthy	None	Heart	Endothelial & interstitial cells	Yes	Immunohistochemical expression	No	None	None	None	Homo sapiens	None	None	10867361	10.1016/s1054-8807(00)00027-2	Upregulation of Adhesion Molecules and Class I HLA in the Myocardium of Chronic Chagasic Cardiomyopathy and Heart Allograft Rejection, But Not in Dilated Cardiomyopathy	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Acute	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Acute	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Acute	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Acute	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Chronic	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Chronic	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Ifng	interferon gamma [Source:MGI Symbol;Acc:MGI:107656]	IFN-Î³	ENSMUSG00000055170	Protein	UP	Chronic	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Acute	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Acute	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Acute	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Chronic	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Chronic	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	BALB/c	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Chronic	Nonesvg	Healthy	None	Spleen cell	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000
Il12b	interleukin 12b [Source:MGI Symbol;Acc:MGI:96540]	IL-12 p40	ENSMUSG00000004296	Protein	UP	Chronic	Nonesvg	Healthy	None	Serum	None	Yes	ELISA	No	None	None	None	Mus musculus	C3H	Tulahuen	10714437	10.1016/s0165-2478(99)00172-8	IL-12 and IFN-gamma production, and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections	2000

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