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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Il4	interleukin 4 [Source:MGI Symbol;Acc:MGI:96556]	IL-4	ENSMUSG00000000869	RNA	UP	Acute	42 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Mmp2	matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009]	MMP-2	ENSMUSG00000031740	Protein	UP	Acute	20 dpisvg	Healthy	None	Heart	None	Yes	ELISA	No	None	None	None	Mus musculus	C57BL/6	Y strain	18444803	10.1086/587487	Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection	2008
Mmp2	matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009]	MMP-2	ENSMUSG00000031740	RNA	UP	Acute	3 dpisvg	Healthy	None	Heart	None	Yes	PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18444803	10.1086/587487	Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection	2008
Mmp9	matrix metallopeptidase 9 [Source:MGI Symbol;Acc:MGI:97011]	MMP-9	ENSMUSG00000017737	RNA	UP	Acute	14 dpisvg	Healthy	None	Heart	None	Yes	PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18444803	10.1086/587487	Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection	2008
Norepinephrine	None	Norepinephrine	None	Protein	DOWN	Chronic	90 dpisvg	Healthy	None	Plasma	None	Yes	reverse-phase HPLC	Yes	None	None	None	Mus musculus	Albino Swiss	SGO-Z12	18582889	10.1016/j.ijpara.2008.04.009	Some components of the cardiac Î²-adrenergic system are altered in the chronic indeterminate form of experimental Trypanosoma cruzi infection	2008
Norepinephrine	None	Norepinephrine	None	Protein	DOWN	Chronic	75 dpisvg	Healthy	None	Plasma	None	Yes	reverse-phase HPLC	Yes	None	None	None	Mus musculus	Albino Swiss	Tulahuen	18582889	10.1016/j.ijpara.2008.04.009	Some components of the cardiac Î²-adrenergic system are altered in the chronic indeterminate form of experimental Trypanosoma cruzi infection	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	7 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	14 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	21 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	28 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	42 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	14 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	21 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	28 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Nos2	nitric oxide synthase 2, inducible [Source:MGI Symbol;Acc:MGI:97361]	iNOS	ENSMUSG00000020826	RNA	UP	Acute	42 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	C57BL/6	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Tgfb1	transforming growth factor, beta 1 [Source:MGI Symbol;Acc:MGI:98725]	TGF-Î²	ENSMUSG00000002603	RNA	UP	Acute	7 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Tgfb1	transforming growth factor, beta 1 [Source:MGI Symbol;Acc:MGI:98725]	TGF-Î²	ENSMUSG00000002603	RNA	UP	Acute	14 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Tgfb1	transforming growth factor, beta 1 [Source:MGI Symbol;Acc:MGI:98725]	TGF-Î²	ENSMUSG00000002603	RNA	UP	Acute	21 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Tgfb1	transforming growth factor, beta 1 [Source:MGI Symbol;Acc:MGI:98725]	TGF-Î²	ENSMUSG00000002603	RNA	UP	Acute	28 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008
Tgfb1	transforming growth factor, beta 1 [Source:MGI Symbol;Acc:MGI:98725]	TGF-Î²	ENSMUSG00000002603	RNA	UP	Acute	42 dpisvg	Healthy	None	Heart	None	Yes	qRT-PCR	No	None	None	None	Mus musculus	BALB/c	Y strain	18473687	10.1086/529527	Inducible nitric oxide synthase and arginase expression in heart tissue during acute Trypanosoma cruzi infection in mice: arginase I is expressed in infiltrating CD68+ macrophages	2008

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