ChagasDB

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Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Cardiac 4 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Cardiac 100 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 48 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 100 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 48 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 100 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 48 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Y strain 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Chronic 100 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Y strain 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Indeterminate 4 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Indeterminate 100 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF tumor necrosis factor ENSG00000232810 Protein UP Severe cardiac Nonesvg Healthy None Plasma None Yes ELISA No None None None Homo sapiens Brazil None 19654138 10.1093/eurjhf/hfp105 Plasma concentrations of tumour necrosis factor-alpha, tumour necrosis factor-related apoptosis-inducing ligand, and FasLigand/CD95L in patients with Chagas cardiomyopathy correlate with left ventricular dysfunction 2009
TNF Tumor Necrosis Factor ENSCAFG00845010558 Protein UP Cardiac 4 weeks pisvg Indeterminate 4 weeks pi PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
TNF tumor necrosis factor ENSG00000232810 Protein UP Severe cardiac Nonesvg Mild cardiac None Plasma None Yes ELISA No None None None Homo sapiens Brazil None 19654138 10.1093/eurjhf/hfp105 Plasma concentrations of tumour necrosis factor-alpha, tumour necrosis factor-related apoptosis-inducing ligand, and FasLigand/CD95L in patients with Chagas cardiomyopathy correlate with left ventricular dysfunction 2009
TNFAIP3 TNF alpha induced protein 3 ENSG00000118503 RNA UP Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFAIP3 TNF alpha induced protein 3 ENSG00000118503 RNA UP Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFAIP3 TNF alpha induced protein 3 ENSG00000118503 RNA UP Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFAIP6 TNF alpha induced protein 6 ENSG00000123610 RNA UP Acute 24h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFAIP6 TNF alpha induced protein 6 ENSG00000123610 RNA UP Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFAIP6 TNF alpha induced protein 6 ENSG00000123610 RNA UP Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
TNFRSF10A TNF receptor superfamily member 10a ENSG00000104689 RNA UP Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
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