ChagasDB

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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
TFDP2	transcription factor Dp-2	TFDP2	ENSG00000114126	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TFE3	transcription factor binding to IGHM enhancer 3	TFE3	ENSG00000068323	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TFEC	transcription factor EC	TFEC	ENSG00000105967	RNA	UP	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TFIP11	tuftelin interacting protein 11	TFIP11	ENSG00000100109	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TFPI2	tissue factor pathway inhibitor 2	TFPI2	ENSG00000105825	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TFRC	transferrin receptor	TFRC	ENSG00000072274	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 C (C/T)	None	Polymorphism	UP	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Colombia	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 C (C/T)	None	Polymorphism	UP	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Colombia + Peru	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 C (C/T)	None	Polymorphism	UP	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Peru	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 T (C/T)	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Colombia	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 T (C/T)	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Colombia + Peru	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB1	transforming growth factor beta 1	TGFÎ²1 10 T (C/T)	None	Polymorphism	DOWN	Chagas	Nonesvg	Healthy	None	Blood	None	Yes	PCR-RFLP	No	None	None	None	Homo sapiens	Peru	None	19136278	10.1016/j.cyto.2008.11.013	Transforming growth factor beta 1 (TGFbeta1) gene polymorphisms and Chagas disease susceptibility in Peruvian and Colombian patients	2009
TGFB2	transforming growth factor beta 2	TGFB2	ENSG00000092969	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TGFB2	transforming growth factor beta 2	TGFB2	ENSG00000092969	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
Tgfb2	transforming growth factor, beta 2 [Source:MGI Symbol;Acc:MGI:98726]	Tgfb2	ENSMUSG00000039239	RNA	DOWN	Acute	46h dpisvg	Healthy	None	Cardiomyocytes	None	No	Microarray	No	None	None	None	Mus musculus	None	Y strain	19729072	10.1016/j.micinf.2009.08.009	Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes	2009
TGFBR1	transforming growth factor beta receptor 1	TGFBR1	ENSG00000106799	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TGIF1	TGFB induced factor homeobox 1	TGIF	ENSG00000177426	RNA	UP	Acute	24h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TGIF1	TGFB induced factor homeobox 1	TGIF	ENSG00000177426	RNA	UP	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
TGM2	transglutaminase 2	TGM2	ENSG00000198959	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
THAP4	THAP domain containing 4	THAP4	ENSG00000176946	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009

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