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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
SPRED2	sprouty related EVH1 domain containing 2	SPRED2	ENSG00000198369	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPRING1	SREBF pathway regulator in golgi 1	C12orf49	ENSG00000111412	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPRY2	sprouty RTK signaling antagonist 2	SPRY2	ENSG00000136158	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	SPSB1	ENSG00000171621	RNA	UP	Acute	24h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	SPSB1	ENSG00000171621	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPSB2	splA/ryanodine receptor domain and SOCS box containing 2	SPSB2	ENSG00000111671	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPSB3	splA/ryanodine receptor domain and SOCS box containing 3	SPSB3	ENSG00000162032	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPSB3	splA/ryanodine receptor domain and SOCS box containing 3	SPSB3	ENSG00000162032	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTBN1	spectrin beta, non-erythrocytic 1	SPTBN1	ENSG00000115306	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTBN1	spectrin beta, non-erythrocytic 1	SPTBN1	ENSG00000115306	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTBN1	spectrin beta, non-erythrocytic 1	SPTBN1	ENSG00000115306	RNA	UP	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTLC2	serine palmitoyltransferase long chain base subunit 2	SPTLC2	ENSG00000100596	RNA	UP	Acute	24h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTLC2	serine palmitoyltransferase long chain base subunit 2	SPTLC2	ENSG00000100596	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTLC2	serine palmitoyltransferase long chain base subunit 2	SPTLC2	ENSG00000100596	RNA	UP	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTLC2	serine palmitoyltransferase long chain base subunit 2	SPTLC2	ENSG00000100596	RNA	UP	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SPTSSA	serine palmitoyltransferase small subunit A	C14orf147	ENSG00000165389	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SQLE	squalene epoxidase	SQLE	ENSG00000104549	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SQOR	sulfide quinone oxidoreductase	SQRDL	ENSG00000137767	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SQOR	sulfide quinone oxidoreductase	SQRDL	ENSG00000137767	RNA	UP	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
SQOR	sulfide quinone oxidoreductase	SQRDL	ENSG00000137767	RNA	UP	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009

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