ChagasDB

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Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
IGFBP7 insulin like growth factor binding protein 7 ENSG00000163453 RNA DOWN Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGSF22 immunoglobulin superfamily member 22 ENSG00000179057 RNA UP Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon ENSG00000263528 RNA UP Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IKZF1 IKAROS family zinc finger 1 ENSG00000185811 RNA UP Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IKZF1 IKAROS family zinc finger 1 ENSG00000185811 RNA UP Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IL10 Interleukin 10 ENSCAFG00845001289 RNA UP Indeterminate 100 weeks pisvg Cardiac 100 weeks pi Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Indeterminate 4 weeks pisvg Cardiac 4 weeks pi PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Indeterminate 100 weeks pisvg Cardiac 100 weeks pi PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 RNA UP Acute Nonesvg Healthy None Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Acute 4 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 RNA UP Acute Nonesvg Healthy None Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Acute 4 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 RNA UP Acute Nonesvg Healthy None Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle Y strain 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Acute 4 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Y strain 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Cardiac 4 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Cardiac 100 weeks pisvg Healthy None PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Chronic 48 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Chronic 100 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle ABC 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 RNA UP Chronic Nonesvg Healthy None Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IL10 Interleukin 10 ENSCAFG00845001289 Protein UP Chronic 48 weeks pisvg Healthy None PBMC None Yes ELISA No None None None Canis lupus familiaris Beagle Berenice-78 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
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