ChagasDB

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Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
Feature name Feature description Feature name in paper Feature ID Feature type Feature variation Phenotype 1 Description phenotype 1 Phenotype 2 Description phenotype 2 Tissue Tissue description Experimental Method Interaction observed Name of the interactive features ID of the interactive features Type of interactive feature Organism Population T.cruzi strain Paper PMID Paper DOI Paper title Paper date
IFNG Interferon Gamma ENSCAFG00845013680 RNA UP Cardiac 100 weeks pisvg Indeterminate 100 weeks pi Heart Right atrium Yes RT-PCR No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IFNG Interferon Gamma ENSCAFG00845013680 Protein UP Cardiac 4 weeks pisvg Indeterminate 4 weeks pi PBMC Right atrium Yes ELISA No None None None Canis lupus familiaris Beagle None 19211152 10.1016/j.vetimm.2009.01.004 Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-gamma, TNF-alpha, and low IL-10 production during the acute infection phase 2009
IFT122 intraflagellar transport 122 ENSG00000163913 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT22 intraflagellar transport 22 ENSG00000128581 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT22 intraflagellar transport 22 ENSG00000128581 RNA DOWN Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT22 intraflagellar transport 22 ENSG00000128581 RNA DOWN Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT27 intraflagellar transport 27 ENSG00000100360 RNA DOWN Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT46 intraflagellar transport 46 ENSG00000118096 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT52 intraflagellar transport 52 ENSG00000101052 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT74 intraflagellar transport 74 ENSG00000096872 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT80 intraflagellar transport 80 ENSG00000068885 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT80 intraflagellar transport 80 ENSG00000068885 RNA DOWN Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFT81 intraflagellar transport 81 ENSG00000122970 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IFTAP intraflagellar transport associated protein ENSG00000166352 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGF1R insulin like growth factor 1 receptor ENSG00000140443 RNA DOWN Acute 24h pisvg Healthy None Human foreskin fibroblasts (HFF) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGF1R insulin like growth factor 1 receptor ENSG00000140443 RNA DOWN Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGF1R insulin like growth factor 1 receptor ENSG00000140443 RNA DOWN Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGFBP4 insulin like growth factor binding protein 4 ENSG00000141753 RNA DOWN Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGFBP6 insulin like growth factor binding protein 6 ENSG00000167779 RNA UP Acute 24h pisvg Healthy None Human cardiac microvascular endothelial cells (HMVEC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
IGFBP6 insulin like growth factor binding protein 6 ENSG00000167779 RNA UP Acute 48h pisvg Healthy None Vascular smooth muscle cells (VSMC) None No Microarray No None None None Homo sapiens None Y strain 19480704 10.1186/1471-2164-10-252 Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling 2009
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