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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
COL12A1	collagen type XII alpha 1 chain	COL12A1	ENSG00000111799	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL13A1	collagen type XIII alpha 1 chain	COL13A1	ENSG00000197467	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL18A1	collagen type XVIII alpha 1 chain	COL18A1	ENSG00000182871	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL1A1	collagen type I alpha 1 chain	COL1A1	ENSG00000108821	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL1A2	collagen type I alpha 2 chain	COL1A2	ENSG00000164692	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL1A2	collagen type I alpha 2 chain	COL1A2	ENSG00000164692	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL3A1	collagen type III alpha 1 chain	COL3A1	ENSG00000168542	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
Col4a2	collagen, type IV, alpha 2 [Source:MGI Symbol;Acc:MGI:88455]	Col4a2	ENSMUSG00000031503	RNA	DOWN	Acute	30h dpisvg	Healthy	None	Cardiomyocytes	None	No	Microarray	No	None	None	None	Mus musculus	None	Y strain	19729072	10.1016/j.micinf.2009.08.009	Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes	2009
COL5A1	collagen type V alpha 1 chain	COL5A1	ENSG00000130635	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL5A3	collagen type V alpha 3 chain	COL5A3	ENSG00000080573	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COL6A1	collagen type VI alpha 1 chain	COL6A1	ENSG00000142156	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
Col6a1	collagen, type VI, alpha 1 [Source:MGI Symbol;Acc:MGI:88459]	Col6a1	ENSMUSG00000001119	RNA	DOWN	Acute	31h dpisvg	Healthy	None	Cardiomyocytes	None	No	Microarray	No	None	None	None	Mus musculus	None	Y strain	19729072	10.1016/j.micinf.2009.08.009	Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes	2009
COL8A1	collagen type VIII alpha 1 chain	COL8A1	ENSG00000144810	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COMMD3	COMM domain containing 3	COMMD3	ENSG00000148444	RNA	DOWN	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
Commd9	COMM domain containing 9 [Source:MGI Symbol;Acc:MGI:1923751]	Commd9	ENSMUSG00000027163	RNA	UP	Acute	96h dpisvg	Healthy	None	Cardiomyocytes	None	No	Microarray	No	None	None	None	Mus musculus	None	Y strain	19729072	10.1016/j.micinf.2009.08.009	Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes	2009
COP1	COP1 E3 ubiquitin ligase	COP1	ENSG00000143207	RNA	UP	Acute	24h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COP1	COP1 E3 ubiquitin ligase	COP1	ENSG00000143207	RNA	UP	Acute	24h pisvg	Healthy	None	Human foreskin fibroblasts (HFF)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COP1	COP1 E3 ubiquitin ligase	COP1	ENSG00000143207	RNA	UP	Acute	24h pisvg	Healthy	None	Human cardiac microvascular endothelial cells (HMVEC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COP1	COP1 E3 ubiquitin ligase	COP1	ENSG00000143207	RNA	UP	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009
COPS2	COP9 signalosome subunit 2	COPS2	ENSG00000166200	RNA	DOWN	Acute	48h pisvg	Healthy	None	Vascular smooth muscle cells (VSMC)	None	No	Microarray	No	None	None	None	Homo sapiens	None	Y strain	19480704	10.1186/1471-2164-10-252	Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling	2009

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