ChagasDB

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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
DDX47	DEAD-box helicase 47	DDX47	cg14057760	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX49	DEAD-box helicase 49	DDX49	cg04673466	Methylation	UP	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX52	DExD-box helicase 52	DDX52	cg05013942	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX54	DEAD-box helicase 54	DDX54	cg15168615	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX6	DEAD-box helicase 6	DDX6	cg05244948	Methylation	DOWN	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX60	DExD/H-box helicase 60	DDX60	cg19252175	Methylation	DOWN	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DDX60L	DExD/H-box 60 like	DDX60L	cg24669389	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DECR2	2,4-dienoyl-CoA reductase 2	DECR2	cg01546397	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEDD2	death effector domain containing 2	DEDD2	cg11721464	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEDD2	death effector domain containing 2	DEDD2	cg14189583	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEDD2	death effector domain containing 2	DEDD2	cg26836479	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEF6	DEF6 guanine nucleotide exchange factor	DEF6	cg10418263	Methylation	DOWN	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEF6	DEF6 guanine nucleotide exchange factor	DEF6	cg15205884	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEF6	DEF6 guanine nucleotide exchange factor	DEF6	ENSG00000023892	RNA	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	RNA-seq	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEF8	differentially expressed in FDCP 8 homolog	DEF8	cg08087034	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEF8	differentially expressed in FDCP 8 homolog	DEF8	cg26894841	Methylation	DOWN	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEFB118	defensin beta 118	DEFB118	cg19453059	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEFB121	defensin beta 121	DEFB121	cg16345789	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEFB121	defensin beta 121	DEFB121	cg26910169	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
DEFB122	defensin beta 122 (pseudogene)	DEFB122	cg01349088	Methylation	DOWN	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022

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