ChagasDB

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Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
Feature name	Feature description	Feature name in paper	Feature ID	Feature type	Feature variation	Phenotype 1	Description phenotype 1	Phenotype 2	Description phenotype 2	Tissue	Tissue description	Experimental	Method	Interaction observed	Name of the interactive features	ID of the interactive features	Type of interactive feature	Organism	Population	T.cruzi strain	Paper PMID	Paper DOI	Paper title	Paper date
CTNNA3	catenin alpha 3	CTNNA3	cg00123238	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNA3	catenin alpha 3	CTNNA3	cg09538287	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNA3	catenin alpha 3	CTNNA3	cg25953715	Methylation	DOWN	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNA3	catenin alpha 3	CTNNA3	cg26160310	Methylation	DOWN	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNA3	catenin alpha 3	CTNNA3	cg01249544	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNA3	catenin alpha 3	CTNNA3	cg08546725	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNAL1	catenin alpha like 1	CTNNAL1	cg09514664	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNAL1	catenin alpha like 1	CTNNAL1	cg05485060	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNAL1	catenin alpha like 1	CTNNAL1	cg06425373	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNAL1	catenin alpha like 1	CTNNAL1	cg21415853	Methylation	DOWN	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
Ctnnb1	catenin (cadherin associated protein), beta 1 [Source:MGI Symbol;Acc:MGI:88276]	Î²-catenin	ENSMUSG00000006932	Protein	DOWN	Acute	1 hpisvg	Healthy	None	Heart endothelia cell	Cell culture	Yes	Immunoblotting assay	No	None	None	None	Mus musculus	None	Tulahuen	34986160	10.1371/journal.pntd.0010074	Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells	2022
Ctnnb1	catenin (cadherin associated protein), beta 1 [Source:MGI Symbol;Acc:MGI:88276]	Î²-catenin	ENSMUSG00000006932	Protein	DOWN	Acute	2 hpisvg	Healthy	None	Heart endothelia cell	Cell culture	Yes	Immunoblotting assay	No	None	None	None	Mus musculus	None	Tulahuen	34986160	10.1371/journal.pntd.0010074	Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells	2022
Ctnnb1	catenin (cadherin associated protein), beta 1 [Source:MGI Symbol;Acc:MGI:88276]	Î²-catenin	ENSMUSG00000006932	Protein	DOWN	Acute	6 hpisvg	Healthy	None	Heart endothelia cell	Cell culture	Yes	Immunoblotting assay	No	None	None	None	Mus musculus	None	Tulahuen	34986160	10.1371/journal.pntd.0010074	Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells	2022
Ctnnb1	catenin (cadherin associated protein), beta 1 [Source:MGI Symbol;Acc:MGI:88276]	Î²-catenin	ENSMUSG00000006932	Protein	DOWN	Acute	6 hpisvg	Healthy	None	Nuclear of heart endothelia cell	Cell culture	Yes	Immunoblotting assay	No	None	None	None	Mus musculus	None	Tulahuen	34986160	10.1371/journal.pntd.0010074	Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells	2022
CTNNBIP1	catenin beta interacting protein 1	CTNNBIP1	cg10035224	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNBIP1	catenin beta interacting protein 1	CTNNBIP1	cg19123622	Methylation	UP	Cardiac	Nonesvg	Asymptomatic	None	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNBIP1	catenin beta interacting protein 1	CTNNBIP1	cg10232889	Methylation	UP	Severe cardiac	LVEF < 40%svg	Moderate cardiac	LVEF >= 40%	Blood	None	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNBL1	catenin beta like 1	CTNNBL1	cg14629475	Methylation	DOWN	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNBL1	catenin beta like 1	CTNNBL1	cg16915477	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022
CTNNBL1	catenin beta like 1	CTNNBL1	cg17974185	Methylation	UP	Cardiac	Nonesvg	Healthy	None	Heart	Left ventricule	No	EPIC Illumina	No	None	None	None	Homo sapiens	Brazil	None	36072583	10.3389/fimmu.2022.958200	Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy	2022

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